Form 4 Tracker
Spyre Therapeutics, Inc.
SYRE

35 insider filings · Latest: Oct 1, 2026

Common Stock Transactions
Txn DateAcceptedInsiderTypeSharesAvg PriceValueShares OwnedFiling
Oct 1, 2026Oct 3 1:30 AMHeidy King-JonesChief Legal Officer and Corporate Secretary
Sale
28,933$91.03$2.6M2,845(D)

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Oct 1, 2026Oct 3 1:29 AMCameron TurtleDirector, Chief Executive Officer
Sale
15,000$92.01$1.4M537,540(D)

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Oct 1, 2026Oct 3 1:29 AMScott L BurrowsChief Financial Officer
Sale
7,500$91.83$688.8K79,762(D)

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Sep 30, 2026Oct 3 1:29 AMScott L BurrowsChief Financial Officer
Sale
17,500$89.89$1.6M79,762(D)

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Oct 1, 2026Oct 1 8:36 PMCAMERON TURTLE
Proposed Sale
45,000$89.03$4.0M—

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Oct 1, 2026Oct 1 8:30 PMHEIDY KING-JONES
Proposed Sale
29,335$89.03$2.6M—

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Sep 30, 2026Sep 30 8:03 PMSCOTT BURROWS
Proposed Sale
17,500$89.89$1.6M—

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Sep 2, 2026Sep 4 1:34 AMHeidy King-JonesOfficer
Sale
400$90.00$36.0K2,845(D)

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Sep 1, 2026Sep 4 1:34 AMHeidy King-JonesOfficer
Sale
27,999$87.31$2.4M2,845(D)

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Sep 2, 2026Sep 4 1:33 AMScott L BurrowsChief Financial Officer
Sale
18,232$89.35$1.6M79,762(D)

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Sep 1, 2026Sep 4 1:33 AMScott L BurrowsChief Financial Officer
Sale
7,500$87.31$654.8K97,994(D)

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Sep 1, 2026Sep 4 1:33 AMCameron TurtleDirector, Chief Executive Officer
Sale
15,000$87.29$1.3M552,540(D)

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Sep 1, 2026Sep 1 8:57 PMHEIDY KING-JONES
Proposed Sale
46,665$89.33$4.2M—

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Aug 7, 2026Aug 11 1:31 AMJeffrey W. AlbersDirector
Sale
23,000$104.53$2.4M9,360(I)

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Aug 7, 2026Aug 7 8:39 PMJEFFREY ALBERS
Proposed Sale
5,000$103.42$517.1K—

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Aug 7, 2026Aug 7 8:39 PMSESSIONS, LLC
Proposed Sale
18,000$103.42$1.9M—

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Aug 3, 2026Aug 6 1:32 AMScott L BurrowsChief Financial Officer
Sale
7,500$95.57$716.8K97,994(D)

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Aug 3, 2026Aug 6 1:31 AMCameron TurtleDirector, Chief Executive Officer
Sale
15,000$95.51$1.4M567,540(D)

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Aug 3, 2026Aug 3 8:51 PMSCOTT BURROWS
Proposed Sale
30,000$98.33$2.9M—

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Jul 1, 2026Jul 3 1:33 AMScott L BurrowsChief Financial Officer
Sale
7,500$87.74$658.0K97,994(D)

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Stock Options & Derivatives
Txn DateAcceptedInsiderTypeSharesExercise PriceShares OwnedFiling
May 1, 2026May 2 1:35 AMScott L BurrowsChief Financial Officer
Option Exercise
12,500$14.50382,357(D)

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May 1, 2026May 2 1:34 AMSheldon SloanChief Medical Officer
Option Exercise
78,333$27.46321,667(D)

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Apr 1, 2026Apr 4 1:30 AMSheldon SloanChief Medical Officer
Option Exercise
7,958$21.6687,542(D)

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Apr 1, 2026Apr 4 1:29 AMScott L BurrowsChief Financial Officer
Option Exercise
7,500$14.50394,857(D)

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Mar 3, 2026Mar 4 2:32 AMScott L BurrowsChief Financial Officer
Option Exercise
2,500$14.50402,357(D)

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